Clinical and therapeutic predictors of disease outcomes in AQP4-IgG + neuromyelitis optica spectrum disorder


Kunchok A., Malpas C., Nytrova P., Havrdova E. K. , Alroughani R., TERZİ M., ...More

MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol.38, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38
  • Publication Date: 2020
  • Doi Number: 10.1016/j.msard.2019.101868
  • Title of Journal : MULTIPLE SCLEROSIS AND RELATED DISORDERS

Abstract

Background: Aquaporin-4-IgG positive (AQP4-IgG(+)) Neuromyelitis Optica Spectrum Disorder (NMOSD) is an uncommon central nervous system autoimmune disorder. Disease outcomes in AQP4-IgG + NMOSD are typically measured by relapse rate and disability. Using the MSBase, a multi-centre international registry, we aimed to examine the impact immunosuppressive therapies and patient characteristics as predictors of disease outcome measures in AQP4-IgG + NMOSD.