Follow-up results of patients with ADCK4 mutations and the efficacy of CoQ10 treatment

Atmaca M., GÜLHAN B., KORKMAZ E., INOZU M., Soylemezoglu O., CANDAN C., ...More

PEDIATRIC NEPHROLOGY, vol.32, no.8, pp.1369-1375, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 8
  • Publication Date: 2017
  • Doi Number: 10.1007/s00467-017-3634-3
  • Journal Name: PEDIATRIC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1369-1375
  • Keywords: Adolescent, Nephrotic syndrome, Chronic kidney disease, ADCK4 mutation, CoQ10 supplementation, NEPHROTIC SYNDROME, STEROID-RESISTANT, REGISTRY, CHILDREN
  • Hacettepe University Affiliated: Yes

Abstract

ADCK4-related glomerulopathy is an important differential diagnosis in adolescents with steroid-resistant nephrotic syndrome (SRNS) and/or chronic kidney disease (CKD) of unknown origin. We screened adolescent patients to determine the frequency of ADCK4 mutation and the efficacy of early CoQ10 administration.