POEMS syndrome: A case report

ÖZDEN A., Sueleyman Z., Seven G., Arat M., Akin A., Sener O., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.19, no.4, pp.276-280, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2008
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.276-280
  • Hacettepe University Affiliated: Yes


A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation. The clinical evaluation met the criteria for the diagnosis of POEMS syndrome. The patient was initially treated with prednisolone and responded well. We planned high-dose chemotherapy with autologous stem cell rescue and introduced a more immunosuppressive regimen containing cyclophosphamide and dexamethasone. We present a case differing from, the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.