Polychlorinated biphenyls and organochlorine pesticides in amniotic fluids of pregnant women in south-central Turkey

DAĞLIOĞLU N., AKÇAN R. , EFEOĞLU P., Inandiklioglu N., GÜLMEN M. K. , Demirhan O.

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, vol.95, no.6, pp.954-961, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 95 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1080/02772248.2013.840370
  • Page Numbers: pp.954-961
  • Keywords: organochlorine pesticides, PCBs, amniotic fluid, exposure, fetus, Cukurova region, CHEMICALS, EXPOSURE, FETAL


The concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in amniotic fluid of 200 pregnant women from the Cukurova region of Turkey. The concentrations of OCPs [hexachlorocyclohexane (HCH), hexachlorobenzene (HCB), dichlorodiphenyl trichloroethane (p,p-DDT), and various metabolites], and different PCB congeners (28, 52, 101, 118, 138, 153, 180) were determined by gas chromatography with electron capture detection as follows: HCB 6.6 +/- 4.7, sigma HCH 21.6 +/- 14.2, sigma DDT 12.5 +/- 7.5, and sigma PCBs 74.0 +/- 54ng mL(-1). Correlations of maternal or gestational age and levels of OCPs and PCBs were not significant. The levels of these organochlorine compounds (OCs) were below detection limit for 5% of the samples, 80% contained more than one OC. This study illustrates that prenatal exposure of a fetus to OCs is prevalent in the Cukurova region.