Polychlorinated biphenyls and organochlorine pesticides in amniotic fluids of pregnant women in south-central Turkey


DAĞLIOĞLU N., AKÇAN R., EFEOĞLU P., Inandiklioglu N., GÜLMEN M. K., Demirhan O.

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, cilt.95, sa.6, ss.954-961, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 95 Sayı: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1080/02772248.2013.840370
  • Dergi Adı: TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.954-961
  • Anahtar Kelimeler: organochlorine pesticides, PCBs, amniotic fluid, exposure, fetus, Cukurova region, CHEMICALS, EXPOSURE, FETAL
  • Hacettepe Üniversitesi Adresli: Evet

Özet

The concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in amniotic fluid of 200 pregnant women from the Cukurova region of Turkey. The concentrations of OCPs [hexachlorocyclohexane (HCH), hexachlorobenzene (HCB), dichlorodiphenyl trichloroethane (p,p-DDT), and various metabolites], and different PCB congeners (28, 52, 101, 118, 138, 153, 180) were determined by gas chromatography with electron capture detection as follows: HCB 6.6 +/- 4.7, sigma HCH 21.6 +/- 14.2, sigma DDT 12.5 +/- 7.5, and sigma PCBs 74.0 +/- 54ng mL(-1). Correlations of maternal or gestational age and levels of OCPs and PCBs were not significant. The levels of these organochlorine compounds (OCs) were below detection limit for 5% of the samples, 80% contained more than one OC. This study illustrates that prenatal exposure of a fetus to OCs is prevalent in the Cukurova region.