Polychlorinated biphenyls and organochlorine pesticides in amniotic fluids of pregnant women in south-central Turkey

DAĞLIOĞLU N., AKÇAN R., EFEOĞLU P., Inandiklioglu N., GÜLMEN M. K., Demirhan O.

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, vol.95, no.6, pp.954-961, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 95 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1080/02772248.2013.840370
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.954-961
  • Keywords: organochlorine pesticides, PCBs, amniotic fluid, exposure, fetus, Cukurova region, CHEMICALS, EXPOSURE, FETAL
  • Hacettepe University Affiliated: Yes


The concentrations of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in amniotic fluid of 200 pregnant women from the Cukurova region of Turkey. The concentrations of OCPs [hexachlorocyclohexane (HCH), hexachlorobenzene (HCB), dichlorodiphenyl trichloroethane (p,p-DDT), and various metabolites], and different PCB congeners (28, 52, 101, 118, 138, 153, 180) were determined by gas chromatography with electron capture detection as follows: HCB 6.6 +/- 4.7, sigma HCH 21.6 +/- 14.2, sigma DDT 12.5 +/- 7.5, and sigma PCBs 74.0 +/- 54ng mL(-1). Correlations of maternal or gestational age and levels of OCPs and PCBs were not significant. The levels of these organochlorine compounds (OCs) were below detection limit for 5% of the samples, 80% contained more than one OC. This study illustrates that prenatal exposure of a fetus to OCs is prevalent in the Cukurova region.