Basal serum tryptase is not a risk factor for immediate-type drug hypersensitivity during childhood

Cavkaytar O., Karaatmaca B., Arik Y., Sahiner Ü. M., Sackesen C., Sekerel B. E., ...More

PEDIATRIC ALLERGY AND IMMUNOLOGY, vol.27, no.7, pp.736-742, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 7
  • Publication Date: 2016
  • Doi Number: 10.1111/pai.12604
  • Journal Name: PEDIATRIC ALLERGY AND IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.736-742
  • Keywords: Anaphylaxis, drug hypersensitivity, pediatrics, tryptase, HYMENOPTERA VENOM ALLERGY, CLINICAL IMMUNOLOGY, PROVOCATION TESTS, EUROPEAN ACADEMY, POSITION PAPER, GENERAL-CONSIDERATIONS, DIAGNOSIS, ANAPHYLAXIS, MANAGEMENT, CHILDREN
  • Hacettepe University Affiliated: Yes

Abstract

Background: High serum basal tryptase (sBT) levels have been identified as a risk factor for both venom-and food-induced severe allergic reactions. The aim of this study was to compare sBT levels in children with different severity of actual drug hypersensitivity reactions (DHRs) with those of age-and sex-matched controls without any history of DHRs.