Primary tumor resection for initially staged IV breast cancer An emphasis on programmed death-ligand 1 expression, promoter methylation status, and survival


Erol T. , İmamoğlu N., Aydin B., Taşkiran Z., Esendağli G. , Kösemehmetoğlu K. , ...Daha Fazla

MEDICINE, cilt.98, sa.33, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Conventional therapy modalities for advanced breast cancer are problematic, whereas checkpoint blockade immunotherapy has been considered as a promising approach. This study aims to determine programmed death-ligand 1 (PD-L1) expression and methylation status of PD-L1 promoter in primary tumor tissue and metastatic foci of patients with stage IV breast cancer.