Inappropriate use of potent topical glucocorticoids in infants

Ozon, ZEYNEP; Cetinkaya, Semra; Alikasifoglu, AYFER; Gonc, E.; Sen, Yasar; Kandemir, NURGÜN

doi:10.1515/jpem.2007.20.2.219

Inappropriate use of potent topical glucocorticoids in infants

Ozon A., Cetinkaya S., Alikasifoglu A., Gonc E. N., Sen Y., Kandemir N.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.20, sa.2, ss.219-225, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 2
Basım Tarihi: 2007
Doi Numarası: 10.1515/jpem.2007.20.2.219
Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.219-225
Hacettepe Üniversitesi Adresli: Evet

Özet

Topical therapy with glucocorticoids (GCs) is used commonly in chronic dermatoses. Side effects are less common compared to systemic us e; however, newer potent preparations may have serious side effects. A potential danger is their inappropriate use. Three infants who developed iatrogenic Cushing's syndrome and prolonged adrenal suppression in the course of GC therapy for simple diaper dermatitis are described. One patient also developed steato-hepatitis which is uncommon with local GCs.