Features of asthma which provide meaningful insights for understanding the disease heterogeneity


Deliu M., Yavuz T. S. , Sperrin M., Belgrave D., Sahiner Ü. M. , Sackesen C. , ...More

CLINICAL AND EXPERIMENTAL ALLERGY, vol.48, no.1, pp.39-47, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1111/cea.13014
  • Title of Journal : CLINICAL AND EXPERIMENTAL ALLERGY
  • Page Numbers: pp.39-47
  • Keywords: allergic sensitization, asthma, childhood, cluster analysis, endotypes, phenotypes, severe asthma, CHILDHOOD ASTHMA, LUNG-FUNCTION, WHEEZE PHENOTYPES, CLUSTER-ANALYSIS, IGE RESPONSES, CHILDREN, ATOPY, CLASSIFICATION, RESPONSIVENESS, POLYMORPHISMS

Abstract

BackgroundData-driven methods such as hierarchical clustering (HC) and principal component analysis (PCA) have been used to identify asthma subtypes, with inconsistent results.