Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study


Quan J., Li X., Chen Y., Jiang Y., Zhou Z., Zhang H., ...More

LANCET INFECTIOUS DISEASES, vol.17, no.4, pp.400-410, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1016/s1473-3099(16)30528-x
  • Title of Journal : LANCET INFECTIOUS DISEASES
  • Page Numbers: pp.400-410

Abstract

Background Polymyxin antibiotics are used as last- resort therapies to treat infections caused by multidrug- resistant Gram- negative bacteria. The plasmid- mediated colistin resistance determinant MCR-1 has been identified in Enterobacteriaceae in China. We did this study to investigate the prevalence of the mcr-1 gene in clinical isolates from patients with bloodstream infections in China.