Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study

Quan, Jingjing; Li, Xi; Chen, Yan; Jiang, Yan; Zhou, Zhihui; Zhang, Huichuan; Sun, Lu; Ruan, Zhi; Feng, Ye; AKOVA, MURAT; Yu, Yunsong

doi:10.1016/s1473-3099(16)30528-x

Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study

Quan J., Li X., Chen Y., Jiang Y., Zhou Z., Zhang H., ...Daha Fazla

LANCET INFECTIOUS DISEASES, cilt.17, sa.4, ss.400-410, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 17 Sayı: 4
Basım Tarihi: 2017
Doi Numarası: 10.1016/s1473-3099(16)30528-x
Dergi Adı: LANCET INFECTIOUS DISEASES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.400-410
Hacettepe Üniversitesi Adresli: Evet

Özet

Background Polymyxin antibiotics are used as last- resort therapies to treat infections caused by multidrug- resistant Gram- negative bacteria. The plasmid- mediated colistin resistance determinant MCR-1 has been identified in Enterobacteriaceae in China. We did this study to investigate the prevalence of the mcr-1 gene in clinical isolates from patients with bloodstream infections in China.