nm23 expression in carcinoma of the uterine cervix

SARAC E., Ayhan A., ERTOY D., Tuncer Z. S., YASUI W., TAHARA E., ...More

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, vol.19, no.3, pp.312-315, 1998 (SCI-Expanded) identifier identifier identifier


To evaluate the significance of nm23 protein expression in cervical carcinoma, 83 patients with stage IB disease, treated primarily with surgery were studied immunohistochemically. Of the cases 57 were squamous carcinoma, 9 were adenocarcinoma, 14 were adenosquamous carcinoma and 3 were small-cell carcinoma. nm23 expression was positive in 63% of the cases. Although positive expression was more common in squamous and adenosquamous type tumors, negative expression was dominant in adenocarcinoma (P<0.05).