Comparison of the effects of melatonin and methylprednisolone in experimental spinal cord injury


Kaptanoglu E., Tuncel M., Palaoglu S., Konan A., Demirpence E., Kilinc K.

JOURNAL OF NEUROSURGERY, vol.93, no.1, pp.77-84, 2000 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 93 Issue: 1
  • Publication Date: 2000
  • Doi Number: 10.3171/spi.2000.93.1.0077
  • Journal Name: JOURNAL OF NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-84
  • Hacettepe University Affiliated: No

Abstract

Object. Melatonin is a very effective antioxidant agent. This study was performed to investigate the effects of melatonin in experimental spinal cord injury (SCI). The authors also compared its effects with those of methylprednisolone, which also protects the spinal cord from secondary injury because of its antioxidant effect on membrane lipids.