The safety of codeine in patients with non-steroidal anti-inflammatory drug hypersensitivity: A preliminary study


Celebioglu E., Karakaya G., Kalyoncu A. F.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.41, no.3, pp.163-168, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1016/j.aller.2012.04.010
  • Title of Journal : ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Page Numbers: pp.163-168

Abstract

Background: Drug provocation testing should be performed before safely prescribing an analgesic for patients that are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs). Whether or not the direct histamine releasing effect of codeine renders it useful in NSAID-hypersensitive patients is unknown. This study aimed to determine if codeine could be recommended as a safe treatment option for NSAID-hypersensitive patients without the need for oral drug provocation testing.