The safety of codeine in patients with non-steroidal anti-inflammatory drug hypersensitivity: A preliminary study
ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.41, no.3, pp.163-168, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 41 Issue: 3
- Publication Date: 2013
- Doi Number: 10.1016/j.aller.2012.04.010
- Journal Name: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.163-168
- Hacettepe University Affiliated: Yes
Abstract
Background: Drug provocation testing should be performed before safely prescribing an analgesic for patients that are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs). Whether or not the direct histamine releasing effect of codeine renders it useful in NSAID-hypersensitive patients is unknown. This study aimed to determine if codeine could be recommended as a safe treatment option for NSAID-hypersensitive patients without the need for oral drug provocation testing.