SURGICAL NEUROLOGY, vol.72, no.2, pp.146-152, 2009 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Atorvastatin, Brain edema, Traumatic brain injury, Lipid peroxidation, DEXAMETHASONE SODIUM-PHOSPHATE, NERVOUS-SYSTEM, NITRIC-OXIDE, CEREBRAL-ISCHEMIA, CORTICAL-NEURONS, BLOOD-FLOW, STROKE, SUPEROXIDE, MECHANISMS, STATINS
Background: The neuroprotective effects of statins possibly depend on their pleiotropic effect such as antioxidative and anti-inflammatory properties. In this study, we have evaluated the efficiency of atorvastatin on brain edema, lipid peroxidation, and ultrastructural changes in TBI animal model.