Evaluation of maternal serum folate, vitamin B12, and homocysteine levels and factor V Leiden, factor II g.20210G > A, and MTHFR variations in prenatally diagnosed neural tube defects
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.46, no.2, pp.489-494, 2016 (Journal Indexed in SCI)
Article / Article
Title of Journal :
TURKISH JOURNAL OF MEDICAL SCIENCES
Background/aim: Neural tube defects (NTDs) are common congenital malformations that develop as a result of interactions between several genes and environmental factors. Many factors have been investigated in order to understand the etiology of NTDs, and many studies have identified folate intake as a common contributing factor. The exact etiology of the disease is still unknown.