Evaluation of maternal serum folate, vitamin B12, and homocysteine levels and factor V Leiden, factor II g.20210G > A, and MTHFR variations in prenatally diagnosed neural tube defects

Aydin, Hatip; Arisoy, Resul; Karaman, Ali; Erdogdu, Emre; Cetinkaya, ARDA; Geçkinli, Bilgen; Simsek, Hasan; Demirci, Oya

doi:10.3906/sag-1502-128

Evaluation of maternal serum folate, vitamin B12, and homocysteine levels and factor V Leiden, factor II g.20210G > A, and MTHFR variations in prenatally diagnosed neural tube defects

Aydin H., Arisoy R., Karaman A., Erdogdu E., Cetinkaya A., Geçkinli B. B., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.46, sa.2, ss.489-494, 2016 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 46 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.3906/sag-1502-128
Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.489-494
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background/aim: Neural tube defects (NTDs) are common congenital malformations that develop as a result of interactions between several genes and environmental factors. Many factors have been investigated in order to understand the etiology of NTDs, and many studies have identified folate intake as a common contributing factor. The exact etiology of the disease is still unknown.