Angiotensin-converting enzyme for noninvasive assessment of liver fibrosis in autoimmune hepatitis


Efe C., Cengiz M. , Kahramanoglu-Aksoy E., YILMAZ B. , Ozseker B., Beyazit Y., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.27, sa.6, ss.649-654, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/meg.0000000000000355
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Sayfa Sayıları: ss.649-654

Özet

Background and aim There are no validated noninvasive markers of liver fibrosis in autoimmune hepatitis (AIH). An activated renin-angiotensin system (RAS) and its key element angiotensin-converting enzyme (ACE) have been implicated in the pathogenesis of hepatic fibrogenesis. We aimed to study the assumed role of activated RAS in the fibrogenic process and whether the serum concentration of ACE can predict different fibrosis stages in AIH.