Angiotensin-converting enzyme for noninvasive assessment of liver fibrosis in autoimmune hepatitis


Efe C., Cengiz M. , Kahramanoglu-Aksoy E., YILMAZ B. , Ozseker B., Beyazit Y., ...More

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.27, no.6, pp.649-654, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1097/meg.0000000000000355
  • Title of Journal : EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Page Numbers: pp.649-654

Abstract

Background and aim There are no validated noninvasive markers of liver fibrosis in autoimmune hepatitis (AIH). An activated renin-angiotensin system (RAS) and its key element angiotensin-converting enzyme (ACE) have been implicated in the pathogenesis of hepatic fibrogenesis. We aimed to study the assumed role of activated RAS in the fibrogenic process and whether the serum concentration of ACE can predict different fibrosis stages in AIH.