Dexmedetomidine reduces the ischemia-reperfusion injury markers during upper extremity surgery with tourniquet

Yagmurdur H., Ozcan N., Dokumaci F., Kilinc K., Yilmaz F., Basar H.

JOURNAL OF HAND SURGERY-AMERICAN VOLUME, sa.6, ss.941-947, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: Sayı: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jhsa.2008.01.014
  • Dergi Adı: JOURNAL OF HAND SURGERY-AMERICAN VOLUME
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.941-947
  • Hacettepe Üniversitesi Adresli: Hayır

Özet

Purpose We examined the effect of dexmedetomidine on ischemia-reperfusion injury due to tourniquet application during upper-extremity surgery by determining blood malondialdehyde and hypoxanthine levels. Alterations in aspartate aminotransferase, alanine aminotransferase, creatine phosphokinase, lactate dehydrogenase, uric acid, and creatinine levels were also assessed.