Can Hyaluronidase Be an Alternative Postoperative Anti-edema Agent to Dexamethasone? Preliminary Results of an Animal Study
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, cilt.76, sa.8, ss.1653-1659, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 76 Sayı: 8
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.joms.2018.03.010
- Dergi Adı: JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1653-1659
- Hacettepe Üniversitesi Adresli: Evet
Özet
Purpose: Recombinant human hyaluronidase (rHuPH20) is widely used as a spreading factor, which enhances the absorption of subcutaneously injected medicines. The anti-inflammatory and anti-edema effects of the enzyme were demonstrated in previous studies. In the present study, the anti-edema effect of rHuPH20 was compared with that of dexamethasone in a traumatic rat paw edema model.