Lung hilar Ga-67 uptake in patients with lymphoma following chemotherapy


Gunay E., Salanci B., Barista I. , Caner B.

ANNALS OF NUCLEAR MEDICINE, cilt.18, sa.5, ss.391-397, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/bf02984482
  • Dergi Adı: ANNALS OF NUCLEAR MEDICINE
  • Sayfa Sayıları: ss.391-397

Özet

Scintigraphic characteristics of lung hilar Ga-67 uptake (HU) and their relationship with the etiology (benign vs. malignant) of the hilar lesions in lymphoma patients following chemotherapy were retrospectively investigated. A total of 161 lymphoma patients were included in the study. ne presence/absence of HU and if present, symmetry/asymmetry and intensity of HU (on the basis of a 3 scale grading system) were visually and semiquantitatively assessed on transaxial sections of thorax Ga-67 SPECT. By drawing ROIs over right and left hilum, asymmetry index (AI%) was also calculated. HU was categorized as benign or malignant depending on the radiological correlation and clinical follow-up. In the malignant group, the majority of patients (85.7%) had grade 2 or grade 3 uptake and all had asymmetric pattern. However, in the benign group, grade 1 uptake was more common (66%) and was mainly symmetric (94.6%) in appearance. AI% in the malignant group (73.7 +/- 36.6) was significantly higher than in the benign group (5.7 +/- 4.9) confirming the marked asymmetry in malignant patients.