Young?s syndrome, a rare syndrome that can cause infertility and mimics cystic fibrosis and immotile-cilia syndrome: a case report

Cihanbeylerden M., Kurt B.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.26, no.18, pp.6569-6571, 2022 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 18
  • Publication Date: 2022
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.6569-6571
  • Keywords: Young?s syndrome, Bronchiectasis, Nasal polyp, Azoospermia, DYSKINESIA
  • Hacettepe University Affiliated: Yes


INTRODUCTION: Young's syn-drome (YS) is a rare, inherited syndrome com-monly seen in middle-aged men with chronic rhinosinusitis, nasal polyps, decreased fertil-ity due to azoospermia, and bronchiectasis. In this paper, we present a case of YS of unknown cause together with a literature review.CASE PRESENTATION: A 28-year-old male patient with the complaints of cough, sputum, recurrent nasal congestion, and shortness of breath lasting for more than ten years, was ad-mitted to our clinic after bronchiectasis was ob-served in the thoracic computed tomography.CONCLUSIONS: An accurate diagnosis of YS is usually made late, which reduces patients' quality of life and leads to chronic respiratory problems. Failure to diagnose this disease may expose the patient to unnecessary and repeated hospitalizations and examinations, and result in treatment failure.