Chitosan-based systems for the delivery of vaccine antigens

Arca H. C. , Guenbeyaz M., ŞENEL S.

EXPERT REVIEW OF VACCINES, vol.8, no.7, pp.937-953, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 8 Issue: 7
  • Publication Date: 2009
  • Doi Number: 10.1586/erv.09.47
  • Title of Journal : EXPERT REVIEW OF VACCINES
  • Page Numbers: pp.937-953


This review discusses the current status of chitosan and its derivatives as adjuvants and delivery systems in vaccine delivery, and their future possibilities and challenges. After a brief introduction to adjuvants and delivery systems, chitosan will be described in detail in regard to vaccine formulation. Applications of chitosan and its derivatives will be reviewed and their proposed mechanisms in the enhancement of immune responses will be discussed.