The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats


Erdem A. , Gundogan N., Usubutun A., Kilinc K., Erdem S., Kara A., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.15, sa.8, ss.1175-1182, 2000 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 15 Konu: 8
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1093/ndt/15.8.1175
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Sayfa Sayıları: ss.1175-1182

Özet

Background. Taurine, which is the major intracellular free beta-amino acid, is known to be an endogenous antioxidant and a membrane-stabilizing agent. In this study, we wished to know whether taurine altered the concentration of gentamicin in kidney tissue and could protect against gentamicin-induced acute proximal tubular injury.