The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats


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Erdem A., Gundogan N., Usubutun A., Kilinc K., Erdem S., Kara A., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.15, sa.8, ss.1175-1182, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 8
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1093/ndt/15.8.1175
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1175-1182
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background. Taurine, which is the major intracellular free beta-amino acid, is known to be an endogenous antioxidant and a membrane-stabilizing agent. In this study, we wished to know whether taurine altered the concentration of gentamicin in kidney tissue and could protect against gentamicin-induced acute proximal tubular injury.