The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats

Erdem, AYŞEN; Gundogan, NU; Usubutun, A; Kilinc, K; Erdem, SR; Kara, A; Bozkurt, ATİLLA

doi:10.1093/ndt/15.8.1175

The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats

Erdem A., Gundogan N., Usubutun A., Kilinc K., Erdem S., Kara A., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.15, sa.8, ss.1175-1182, 2000 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15 Sayı: 8
Basım Tarihi: 2000
Doi Numarası: 10.1093/ndt/15.8.1175
Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1175-1182
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Background. Taurine, which is the major intracellular free beta-amino acid, is known to be an endogenous antioxidant and a membrane-stabilizing agent. In this study, we wished to know whether taurine altered the concentration of gentamicin in kidney tissue and could protect against gentamicin-induced acute proximal tubular injury.