This paper aims to bring up the most prevalent pneumococcal. serotypes and serogroups detected in recent Turkish studies. The current PCV-7 formulation covers only 37% of IPI in Turkey and if serotypes /groups 4, 6V, 9B, 18C in the current formulation are replaced with 1, 3, 6B and 9A in PCV-7, then the vaccination coverage will increase up to 64%, an improvement that is significant statistically. Similarty, if 11 A, 12F, 1513, 17F and 22F are substituted with 6A, 9A, 9L, 19C and 23B in existing PPV-23, the new formulation wilt increase coverage up to 95% for Turkish population. (C) 2007 Elsevier Ltd. AU rights reserved.