Real-life outcomes of unselected acute promyelocytic leukemia patients: a single-center 14-year experience

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Akcay O. F., YETER H. H., BÜYÜKAŞIK Y.

ROMANIAN JOURNAL OF INTERNAL MEDICINE, vol.58, no.3, pp.138-145, 2020 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.2478/rjim-2020-0011
  • Journal Name: ROMANIAN JOURNAL OF INTERNAL MEDICINE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.138-145
  • Hacettepe University Affiliated: Yes

Abstract

Background. After the inclusion of all-trans retinoic acid (ATRA) into the treatment of Acute Promyelocytic leukemia (APL), a notable improvement concerning the survival rates of patients with APL has been observed. However, the population-based studies demonstrated that there was no marked improvement in the survival of patients after the 2000s. We aim to describe the clinical response and prognosis of adult patients diagnosed with APL and examine the change in these outcomes by the time period of diagnosis.