Real-life outcomes of unselected acute promyelocytic leukemia patients: a single-center 14-year experience


Akcay O. F. , YETER H. H. , BÜYÜKAŞIK Y.

ROMANIAN JOURNAL OF INTERNAL MEDICINE, cilt.58, sa.3, ss.138-145, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 58 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2478/rjim-2020-0011
  • Dergi Adı: ROMANIAN JOURNAL OF INTERNAL MEDICINE
  • Sayfa Sayıları: ss.138-145

Özet

Background. After the inclusion of all-trans retinoic acid (ATRA) into the treatment of Acute Promyelocytic leukemia (APL), a notable improvement concerning the survival rates of patients with APL has been observed. However, the population-based studies demonstrated that there was no marked improvement in the survival of patients after the 2000s. We aim to describe the clinical response and prognosis of adult patients diagnosed with APL and examine the change in these outcomes by the time period of diagnosis.