Real-life outcomes of unselected acute promyelocytic leukemia patients: a single-center 14-year experience


Akcay O. F. , YETER H. H. , BÜYÜKAŞIK Y.

ROMANIAN JOURNAL OF INTERNAL MEDICINE, vol.58, no.3, pp.138-145, 2020 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.2478/rjim-2020-0011
  • Title of Journal : ROMANIAN JOURNAL OF INTERNAL MEDICINE
  • Page Numbers: pp.138-145

Abstract

Background. After the inclusion of all-trans retinoic acid (ATRA) into the treatment of Acute Promyelocytic leukemia (APL), a notable improvement concerning the survival rates of patients with APL has been observed. However, the population-based studies demonstrated that there was no marked improvement in the survival of patients after the 2000s. We aim to describe the clinical response and prognosis of adult patients diagnosed with APL and examine the change in these outcomes by the time period of diagnosis.