High-dose methylprednisolone treatment of hepatic veno-occlusive disease in a child with Wilms tumor


Akyuz C. , Caelar K., Emir S., Buyukpamukcu M.

PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.20, sa.4, ss.345-349, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1080/08880010390203080
  • Dergi Adı: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Sayfa Sayıları: ss.345-349

Özet

Veno-occlusive disease (VOD) is a rare complication of chemotherapy in children with cancer. In the literature successful treatment of severe VOD has not been well determined. The authors report a 5-year-old boy with Willms tumor whose condition was complicated with VOD while receiving chemotherapy. He was treated successfully with high-dose methylprednisolone. After therapy, the clinical signs of VOD, such as abdominal ascites, oliguria, and jaundice, disappeared without any adverse effects of therapy.