Aquaporin-4 expression is not elevated in mild hydrocephalus

Aghayev K., Bal E., Rahimli T., Mut M., Balci S., Vrionis F., ...Daha Fazla

Acta Neurochirurgica, cilt.154, sa.4, ss.753-759, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 154 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00701-011-1241-9
  • Dergi Adı: Acta Neurochirurgica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.753-759
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Aquaporin-4 (aqp-4) is a member of water channel family proteins primarily expressed in the central nervous system. Physiologically it is the main channel providing water transport into the nervous system water compartments and across the blood-brain barrier. Several studies demonstrated its compensatory role in severe hydrocephalus. However, its role is not clear during the initial stages of hydrocephalus.