Aquaporin-4 expression is not elevated in mild hydrocephalus

Aghayev K., Bal E., Rahimli T., Mut M. , Balci S., Vrionis F., ...Daha Fazla

Acta Neurochirurgica, cilt.154, sa.4, ss.753-759, 2012 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 154 Konu: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00701-011-1241-9
  • Dergi Adı: Acta Neurochirurgica
  • Sayfa Sayıları: ss.753-759


Aquaporin-4 (aqp-4) is a member of water channel family proteins primarily expressed in the central nervous system. Physiologically it is the main channel providing water transport into the nervous system water compartments and across the blood-brain barrier. Several studies demonstrated its compensatory role in severe hydrocephalus. However, its role is not clear during the initial stages of hydrocephalus.