Increased Serum Nesfatin-1 Levels in Patients with Impaired Glucose Tolerance

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Akin S., Gulcelik N. E., Aksoy D. Y., Karakaya J., Usman A.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, vol.21, no.3, pp.65-67, 2017 (ESCI)

• Publication Type: Article / Article
• Volume: 21 Issue: 3
• Publication Date: 2017
• Doi Number: 10.25179/tjem.2017-56543
• Journal Name: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.65-67
• Hacettepe University Affiliated: Yes

Abstract

Purpose: Nesfatin-1 is a recently discovered energy-regulating peptide, widely expressed in both central and peripheral tissues. It is involved in various functions, such as the stimulation of hypothalamic-pituitary-adrenal axis and sympathetic nervous system, influencing visceral functions, water intake, and regulation of temperature and emotions. It exerts a direct glucose-dependent insulinotropic action on the beta cells of pancreatic islets. The current study evaluated nesfatin-1 levels and insulin response to glucose load in patients with impaired glucose tolerance (IGT) and in healthy subjects.