Interferon-gamma assays for the diagnosis of tuberculosis infection before using tumour necrosis factor-alpha blockers

Cobanoglu, N.; Ozcelik, KADRİYE; Kalyoncu, U.; Ozen, S.; Kiraz, S.; Gurcan, N.; Kaplan, M.; Dogru, DENİZ; Yalcin, E.; Pekcan, S.; Kose, M.; Topaloglu, Ft.; Besbas, NESRİN; Bakkaloglu, AYŞİN; Kiper, N.

Interferon-gamma assays for the diagnosis of tuberculosis infection before using tumour necrosis factor-alpha blockers

Cobanoglu N., Ozcelik U., Kalyoncu U., Ozen S., Kiraz S., Gurcan N., ...Daha Fazla

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, cilt.11, sa.11, ss.1177-1182, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 11 Sayı: 11
Basım Tarihi: 2007
Dergi Adı: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1177-1182
Hacettepe Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Patients who receive tumour necrosis factor-alpha (TNF-alpha) blockers are mostly immunosuppressed. A study was performed to investigate whether an interferon-gamma (IFN-gamma) assay could rep-resent an alternative approach to the tuberculin skin test (TST) for the diagnosis of latent tuberculosis infection (LTBI) in these patients.