Antimicrobial Activity 4-Substituted-Styryl-2-Azetidinone

Gürsoy V.

Journal of Pharmaceutical Chemistry , vol.2, no.1, pp.11-15, 2005 (ESCI)

  • Publication Type: Article / Article
  • Volume: 2 Issue: 1
  • Publication Date: 2005
  • Journal Name: Journal of Pharmaceutical Chemistry
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.11-15
  • Hacettepe University Affiliated: Yes

Abstract

In this study, antimicrobial activity of previously synthesized 1-(Substituted phenyl)-4-(substituted styryl)-2-azetidinones(3a-i) have been examined. All compounds have been tested against Gram(+) and Gram(-) bacteria and yeasts. It was found that activity is not significantly influenced by the substituents on the ring. Özet Bu çalismada, daha onceden sentezleri yapilan 1-(substitutefenil)-4-(substituestril)-2-azetidinonlarin (3a-i) antimikrobiyal aktiviteleri incelenmistir. Bütün bilesikler Gram (+) ve Gram (-) bakterilere ve mayaya karsi test edilmistir. Aktivite, halkadaki substituentlerden önemli derecede etkilenmedigi bulundu.