AA type renal amyloidosis secondary to FMF: a long-term follow-up in two patients

Kutlugun A. A., YILDIRIM T., Altindal M., ARICI M., Yasavul U., Turgan C.

RENAL FAILURE, vol.32, no.10, pp.1230-1232, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 10
  • Publication Date: 2010
  • Doi Number: 10.3109/0886022x.2010.517344
  • Journal Name: RENAL FAILURE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1230-1232
  • Hacettepe University Affiliated: Yes


Renal amyloidosis, which leads to renal failure, is the most important long-term complication of familial Mediterranean fever (FMF). Resolution of nephrotic syndrome secondary to amyloidosis in FMF following colchicine treatment has rarely been reported. We describe two patients with FMF and nephrotic syndrome. These patients were treated with colchicine 1.5 mg/day and had a complete remission of nephrotic syndrome with a stable clinical course over 30 years. To our knowledge, our patients have the longest follow-up time without proteinuria.