Association between Tumor Characteristics and Bone Mineral Density in Postmenopausal Breast Cancer Patients

Creative Commons License

Bayraktar S., Avery T., Altundag K., Broglio K., Arun B. K.

BREAST JOURNAL, vol.19, no.4, pp.431-434, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1111/tbj.12141
  • Journal Name: BREAST JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.431-434
  • Hacettepe University Affiliated: Yes


The aim of this study was to evaluate the association of bone mineral density (BMD) at the time of diagnosis with clinical-pathologic findings in patients with operable postmenopausal breast cancer. One hundred and fifty-eight postmenopausal women who had a baseline lumbar and hip BMD measurement were included in the analysis. Patients were divided into two groups based on the median BMD. p0.002 was considered to be statistically significant. Hormone replacement therapy (HRT) use longer than 5years was associated with increased lumbar BMD compared with patients who used HRT less than 5years (p=0.002). Patients with higher BMD tended to have low grade disease, no lympho-vascular invasion, progesterone receptor-positive tumors, and low Ki-67 levels (p<0.05). Higher baseline BMD in postmenopausal patients with breast cancer is associated with favorable prognostic features.