Dielectric barrier discharge and jet type plasma surface modifications of hybrid polymeric poly (epsilon-caprolactone)/chitosan scaffolds


Ozkan O., TÜRKOĞLU ŞAŞMAZEL H.

JOURNAL OF BIOMATERIALS APPLICATIONS, cilt.32, ss.1300-1313, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 9
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1177/0885328218755571
  • Dergi Adı: JOURNAL OF BIOMATERIALS APPLICATIONS
  • Sayfa Sayıları: ss.1300-1313

Özet

In this study, dry air plasma jet and dielectric barrier discharge Ar+O-2 or Ar+N-2 plasma modifications and their effects on wettability, topography, functionality and biological efficiency of the hybrid polymeric poly (epsilon-caprolactone)/chitosan scaffolds were reported. The samples treated with Ar+O-2 dielectric barrier discharge plasma (80 sccm O-2 flow rate, 3-min treatment) or with dry air plasma jet (15-cm nozzle-sample distance, 13-min treatment) had the closest wettability (49.11 +/- 1.83 and 53.60 +/- 0.95, respectively) to the commercial tissue culture polystyrene used for cell cultivation. Scanning electron microscopy images and X-ray photoelectron spectrometry analysis showed increase in topographical roughness and OH/NH2 functionality, respectively. Increased fluid uptake capacity for the scaffolds treated with Ar+O-2 dielectric barrier discharge plasma (73.60%+/- 1.78) and dry air plasma jet (72.48%+/- 0.75) were also noted. Finally, initial cell attachment as well as seven-day cell viability, growth and proliferation performances were found to be significantly better for both plasma treated scaffolds than for untreated scaffolds.