Effects of calcitonin, risedronate, and raloxifene on erythrocyte antioxidant enzyme activity, lipid peroxidation, and nitric oxide in postmenopausal osteoporosis

Ozgocmen S., Kaya H., Fadillioglu E. , Yilmaz Z.

ARCHIVES OF MEDICAL RESEARCH, vol.38, no.2, pp.196-205, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1016/j.arcmed.2006.09.010
  • Title of Journal : ARCHIVES OF MEDICAL RESEARCH
  • Page Numbers: pp.196-205

Abstract

Background. The aims of this study were to compare erythrocyte antioxidant enzyme activities, lipid peroxidation, and nitric oxide levels (NO) in women with postmenopausal osteoporosis (PMO) and non-porotic postmenopausal healthy controls and to assess the relationship between bone mineral density and these oxidant/antioxidant parameters. Additionally, in vivo effects of three different anti-osteoporotic drugs, calcitonin, risedronate and raloxifene, on the erythrocyte oxidant-antioxidant status in women with PMO were also assessed.