In clinical drug trials it is essential in terms of Medical ethics to study on patient's and subject's rights, to discuss on physician-investigator/patient-subject relations, and to evaluate the dynamics inherited within these relations. In order to have internationally acceptable trials, besides the existence of methodological and semantical harmony, it is also necessary to standardize ethical principles, as well. For different societies in which production of scientific knowledge take place, it is possible to speak about the existence of different cultural factors. On the other hand, free from the fact that to what extent they differ from each other regarding the level of economical and sociological development, there should be some "universal ethical principles" binding scientists from different geographies of the world. In Medical researches the term "universality" has started to be cited more, and it has been obvious that a common consideration on basic values that direct these researches is needed. Only when these are taken into account, the researches that are conducted in different countries may have the same level of scientific and ethical standards. Since, the patient-physician relations in Turkish society and its reflections on clinical drug trials, and regulations about clinical drug trials in Turkey should be evaluated.