The factor V Leiden mutation: A possible contributor to the hepatic artery thrombosis encountered after liver transplantation in a child

Tanyel F. C., Ocal T., Balkanci F., Cekirge S., Senocak M., Buyukpamukcu N., ...More

JOURNAL OF PEDIATRIC SURGERY, vol.35, no.4, pp.607-609, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 4
  • Publication Date: 2000
  • Doi Number: 10.1053/jpsu.2000.0350607
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.607-609
  • Hacettepe University Affiliated: Yes


A 10-year-old girl has experienced 3 recurrences of hepatic artery thrombosis (HAT) after a liver transplantation. She responded to intraarterial administrations of urokinase after the first 2 attacks. However, the restoration of the arterial flow was not possible after the third attack. The child and her father were both heterozygous for factor V Leiden mutation. In addition to the technical factors, the factor V Leiden mutation should be considered as a factor that plays a role in HAT. Copyright (C) 2000 by W.B. Saunders Company.