The Ameliorative Effects of Pycnogenol (R) on Liver Ischemia-Reperfusion Injury in Rats


Tokac M., BACANLI M. , DUMLU E. G. , AYDIN DİLSİZ S. , Engin M., BOZKURT B., ...More

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.14, no.3, pp.257-263, 2017 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.4274/tjps.49369
  • Title of Journal : TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Page Numbers: pp.257-263

Abstract

Objectives: Pycnogenol (R) (PYC (R)), a standardized extract from the bark of Pinus maritima, consists of different phenolic compounds. PYC (R) has shown to have protective effects on chronic diseases such as diabetes, asthma, cancer, and immune disorders. The aim of this study was to determine the effects of PYC (R) against the DNA damage and biochemical changes in blood, liver, and lung tissues of ischemia-reperfusion (IR)-induced Wistar albino rats.