Transformation of Adult Myelodysplastic Syndrome-Refractory Anemia to Acute T-Cell Lymphoblastic Leukemia


Serefhanoglu S., GÖKER H., BÜYÜKAŞIK Y., SAYINALP N., ÖZCEBE O. İ.

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.101, sa.4, ss.370-372, 2009 (SCI-Expanded) identifier identifier

Özet

Objective: Myelodysplastic syndrome (MDS) is recognized as a preleukemic disorder with a variable risk of transformation to acute myeloid leukemia. Usually the blast cells in leukemia are transformed after MDS displays a myeloid phenotype. Lymphoid progression had been reported as myeloid-lymphoid hybrid or early B phenotype, but our patient transformed acute T-lymphoblastic leukemia, which is a rare lymphoid transformation.