Transformation of Adult Myelodysplastic Syndrome-Refractory Anemia to Acute T-Cell Lymphoblastic Leukemia

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Serefhanoglu S., GÖKER H., BÜYÜKAŞIK Y., SAYINALP N., ÖZCEBE O. İ.

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, vol.101, no.4, pp.370-372, 2009 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 101 Issue: 4
• Publication Date: 2009
• Doi Number: 10.1016/s0027-9684(15)30887-7
• Journal Name: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.370-372
• Hacettepe University Affiliated: Yes

Abstract

Objective: Myelodysplastic syndrome (MDS) is recognized as a preleukemic disorder with a variable risk of transformation to acute myeloid leukemia. Usually the blast cells in leukemia are transformed after MDS displays a myeloid phenotype. Lymphoid progression had been reported as myeloid-lymphoid hybrid or early B phenotype, but our patient transformed acute T-lymphoblastic leukemia, which is a rare lymphoid transformation.