Molecular imprinted polymer based electrochemical sensor for selective detection of paraben

Yucebas B. B., YAMAN Y. T., BOLAT G., ÖZGÜR E., UZUN L., ABACI S.

SENSORS AND ACTUATORS B-CHEMICAL, cilt.305, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 305
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.snb.2019.127368
  • Dergi Adı: SENSORS AND ACTUATORS B-CHEMICAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Analytical Abstracts, Biotechnology Research Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Pollution Abstracts, Civil Engineering Abstracts
  • Anahtar Kelimeler: Molecular imprinted polymer, Paraben, Electrochemical sensor, PERFORMANCE LIQUID-CHROMATOGRAPHY, ESTROGENIC ACTIVITY, COSMETIC PRODUCTS, CARBON ELECTRODE, LABEL-FREE, METHYLPARABEN, SAMPLES, MICROEXTRACTION, NANOPARTICLES, EXTRACTION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A new, simple, rapid, sensitive and selective disposable sensor platform was developed for the electrochemical detection of paraben based on molecular imprinting technique. Highly selective and specific recognition was established for the analyte through incorporating amino acid based polymerizable functional monomer. Paraben-imprinted poly-(2-hydroxyethyl methacrylate-N-methacryloyl-L-phenylalanine) (PHEMA-MAPA) nanofilm on a screen-printed gold electrode surface in the presence of polyvinyl alcohol (PVA) was synthesized by the molecular imprinting technique. Characterization of the fabricated electrode surfaces were performed with cyclic voltammetry (CV), atomic force microscopy (AFM) and attenuated total reflection fourier transform infrared spectrophotometry (ATR FT-IR). The electrochemical behavior of paraben was investigated using CV and electrochemical detection studies were carried out with square wave voltammetry (SWV). Under optimal conditions, the linear working range was found to be 1-30 mu M with a low detection limit as 0.706 mu M. The obtained recovery values proved that the developed sensor can be effectively applied to cosmetic samples. Besides, the fabricated disposable sensor system can be used successfully in the determination of other important analytes in the future due to its good sensor performance.