Analysis of the relationship between the severity of periodontal destruction and proteoglycan metabolism of gingiva and gingival crevicular fluid


Huri C., Yamalik N., Kilinc K., Kilinc A., Etikan I., Eratalay K.

JOURNAL OF CLINICAL PERIODONTOLOGY, vol.30, no.11, pp.961-968, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 11
  • Publication Date: 2003
  • Doi Number: 10.1034/j.1600-051x.2003.00408.x
  • Journal Name: JOURNAL OF CLINICAL PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.961-968
  • Keywords: GCF, gingiva, proteoglycan, periodontal destruction, MOLECULAR-SIZE DISTRIBUTION, INFLAMMATORY MEDIATORS, GLYCOSAMINOGLYCANS, PATHOGENESIS, DIAGNOSIS, ENZYMES, DISEASES
  • Hacettepe University Affiliated: Yes

Abstract

Background: Although it is well-described that proteoglycans (PGs) are among the major non-collagenous components of the matrix which are degraded during periodontal diseases, the relationship between PG metabolism and seventy of periodontal breakdown, the extent of degradation of PGs together with the resulting end-products, and the elimination pathways of these catabolic end-products is likely to need further clarification.