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Bachimam K., Emul E., SAĞLAM N., KORKUSUZ F.
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.50, no.4, pp.1139-1146, 2020 (SCI-Expanded)
Article / Article
TURKISH JOURNAL OF MEDICAL SCIENCES
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
Baicalein, hyaluronic acid, nanofiber, electrospinning, bone cancer, tissue engineering, BONE, DIFFERENTIATION, OSTEOSARCOMA, ACTIVATION, MIGRATION, DELIVERY
Hacettepe University Affiliated:
Background/aim: Bone tumor is one of the major causes of tissue bone loss, particularly after performing surgical excision operation to bone lesion that needs to be replaced by biomaterials and ensure a complete filling of tissue-loss spaces. The purpose of our study was to produce a nanofiber-based bone graft scaffold to fill the gaps resulted from bone cancer treatment and also capable of carrying functional molecules that can play a major role in preventing further cancer growth at the targeted bone tissue.