Biofunctionalization of cellulosic fibres with L-cysteine: Assessment of antibacterial properties and mechanism of action against Staphylococcus aureus and Klebsiella pneumoniae


Creative Commons License

Caldeira E., Piskin E., Granadeiro L., Silva F., Gouveia I. C.

JOURNAL OF BIOTECHNOLOGY, vol.168, no.4, pp.426-435, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 168 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1016/j.jbiotec.2013.10.021
  • Journal Name: JOURNAL OF BIOTECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.426-435
  • Hacettepe University Affiliated: Yes

Abstract

The main purpose of this work is to obtain a cotton-based textile material functionalized with L-cysteine (L-cys) to achieve an antimicrobial effect with potential application in biomedical, geriatric or pediatric textiles. The binding capacity of L-cys to cotton fibres was assessed through different functionalization strategies surface activation and exhaustion processes. A subsequent analysis of the possible antibacterial action against Staphylococcus aureus and Klebsiella pneumoniae was performed according with the Japanese International standard (JISL, 2008). To determine the mechanism of action of L-cys on the selected strains, flow cytometry was used.