The Increased Frequency of Familial Mediterranean Fever in Patients Diagnosed with Immunoglobulin a Vasculitis (Henoch-Schonlein Purpura)

Sonmez H. E., Batu E. D., Bilginer Y.

GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS, cilt.16, sa.1, ss.35-46, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 1
  • Basım Tarihi: 2018
  • Dergi Adı: GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.35-46
  • Hacettepe Üniversitesi Adresli: Evet

Özet

INTRODUCTION: Immunoglobulin A vasculitis/Henoch Schonlein purpura (IgAV/HSP) is the most common vasculitis in childhood. It is characterized by non-thrombocytopenic purpura, abdominal pain, gastrointestinal bleeding, arthritis or arthralgia and nephritis. Familial Mediterranean fever (FMF), is the most common autoinflammatory disease, manifesting with recurrent fever episodes and serositis. In this study, we aimed to determine the general characteristics and MEFV (Mediterranean FeVer) mutation occurrence rate in patients diagnosed with IgAV/HSP and to compare the clinical, laboratory and treatment characteristics of cases with FMF+IgAV/HSP and cases with only IgAV/HSP.