Comparison of the effects of continuous and intermittent portal triad occlusion (PTO) in rats


Ozmen M., Oruc M., Besler H., Kulah B., Safali M., Polat A., ...More

HEPATO-GASTROENTEROLOGY, vol.50, no.54, pp.2127-2132, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 54
  • Publication Date: 2003
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2127-2132
  • Hacettepe University Affiliated: No

Abstract

Background/Aims: It has previously been shown that prolonged ischemia of the liver had a mortal course and a method of intermittent occlusion of the hepatic pedicle was defined in order to minimize the damage to the liver. The present experimental study aimed to compare the effects of continuous and intermittent occlusion of the hepatic pedicle on the liver by measuring serum lactate, serum MDA malondialdehyde and glutathione levels and by evaluating the histologic changes in the liver tissue.