An unusual case of urinary tract infection caused by Saprochaete capitata under anidulafungin treatment

HAZIROLAN G., AYPAK a., AKSU n.

JOURNAL DE MYCOLOGIE MEDICALE, cilt.27, sa.3, ss.387-390, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.mycmed.2017.04.001
  • Dergi Adı: JOURNAL DE MYCOLOGIE MEDICALE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.387-390
  • Anahtar Kelimeler: Saprochaete capitata, Urinary tract infection, MALDI TOF MS, DNA sequencing analysis, Antifungal susceptibility, DESORPTION IONIZATION-TIME, FLIGHT MASS-SPECTROMETRY, OF-THE-LITERATURE, BLASTOSCHIZOMYCES-CAPITATUS, MAGNUSIOMYCES-CAPITATUS, GEOTRICHUM-CAPITATUM, EMERGENCE, PATIENT, CANCER
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Saprochaete capitata may cause uncommon severe infections, especially in immunocompromised patients. Here, we describe a rare case of urinary tract infection by S. capitata in a chronic kidney disease and diabetes mellitus patient, which occur during anidulafungin therapy. Mycological examinations of urine were positive to S. capitata identified by mass spectrometry and confirmed by ITS sequencing. Minimum inhibitory concentration (MIC) of the isolate for amphotericin B, fluconazole, itraconazole, voriconazole and, anidulafungin were 2, 16, 1, 1, and 8 mu g/mL, respectively. Presence of S. capitata infection was not known. Clinicians should be aware about these rare opportunistic fungal pathogens, particularly those with intrinsic or variable resistance to antifungals including echinocandins. (C) 2017 Elsevier Masson SAS. All rights reserved.