Hyperhomocysteinemia is associated with the presence of left atrial thrombus in stroke patients with nonvalvular atrial fibrillation

AY H., Arsava E. M., Tokgozoglu S. L., Ozer N., SARIBAS O.

STROKE, vol.34, no.4, pp.909-912, 2003 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1161/01.tr.0000060202.63475.ba
  • Journal Name: STROKE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.909-912
  • Hacettepe University Affiliated: Yes

Abstract

Background and Purpose-Blood stasis is the fundamental mechanism leading to thrombus formation in the venous system. Homocysteine also poses a significant risk for venous thrombosis through its endothelial toxic and prothrombotic properties. In the present study, we hypothesized that high homocysteine might be associated with thrombus formation in another stasis-related condition, atrial fibrillation.