In Vitro Biocompatibility of n-Type and Undoped Silicon Nanowires

Garipcan B., Odabas S., Demirel G., Burger J., Nonnenmann S. S., Coster M. T., ...Daha Fazla

ADVANCED ENGINEERING MATERIALS, cilt.13, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 13
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1002/adem.200980045
  • Dergi Adı: ADVANCED ENGINEERING MATERIALS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Hacettepe Üniversitesi Adresli: Evet

Özet

The biocompatibility of undoped and n-type silicon nanowires (SiNWs), synthesized by metal-catalyzed chemical vapor deposition, was investigated in vitro, and compared with that for SiO(2)-coated silicon wafers. In cell interaction studies, L929 mouse fibroblast cells were used, in which MTT assay, AO/PI dye staining, cell proliferation/growth, and changes in cell adhesion/morphology on the surfaces were applied and investigated. Heamocompatibility of these materials were also tested. No significant cytotoxic effects were observed for either the undoped or for the n-type phosphorus-doped SiNWs. The cells on the nanowires exhibit high viability, normal nuclear, and morphological structure. They have shown no considerable negative blood response with respect to the control.