Late Onset and Protracted Course of Steroid Refractory Chronic Graft-versus-Host Disease

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GÜNEŞ G., DEMİROĞLU H., GÖKER H., Malkan Ü. Y., ELİAÇIK E., Yayar O., ...More

CASE REPORTS IN HEMATOLOGY, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2015
  • Doi Number: 10.1155/2015/692175
  • Journal Name: CASE REPORTS IN HEMATOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Hacettepe University Affiliated: Yes

Abstract

Chronic graft-versus-host disease (cGVHD) is one of the most important causes of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (aHSCT). Occurring in 30% to 70% of patients, cGVHD has a median time to onset of 4 to 6 months and most cases present within 2 years after aHSCT. Here, we present a patient transplanted at the age of 55 who developed refractory cutaneous cGVHD more than 5.5 years after aHSCT.