Analysis of Cathepsin-K Activity at Tooth and Dental Implant Sites and the Potential of This Enzyme in Reflecting Alveolar Bone Loss

YAMALIK N., Gunday S., UYSAL S., Kilinc K., KARABULUT E., TÖZÜM T. F.

JOURNAL OF PERIODONTOLOGY, vol.83, no.4, pp.498-505, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 83 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1902/jop.2011.110232
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.498-505
  • Keywords: Alveolar bone loss, cathepsin K, dental implants, inflammation, tooth, GINGIVAL CREVICULAR FLUID, NITRIC-OXIDE METABOLISM, FOLLOW-UP, MATRIX METALLOPROTEINASES, EDENTULOUS PATIENTS, NATURAL TEETH, PERIODONTITIS, IMPACT, DISEASE, MYELOPEROXIDASE
  • Hacettepe University Affiliated: Yes

Abstract

Background: Cathepsin-K is an enzyme involved in bone metabolism which may make this feature important for both natural teeth and dental implants. The aims of the present study are to comparatively analyze the gingival crevicular fluid (GCF)/peri-implant sulcus fluid (PISF) cathepsin-K levels of natural teeth and dental implants, and to assess the potential relationship between this biochemical parameter and alveolar bone loss around natural teeth and dental implants.