Analysis of Cathepsin-K Activity at Tooth and Dental Implant Sites and the Potential of This Enzyme in Reflecting Alveolar Bone Loss

YAMALIK N., Gunday S., UYSAL S., Kilinc K., KARABULUT E., TÖZÜM T. F.

JOURNAL OF PERIODONTOLOGY, cilt.83, sa.4, ss.498-505, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1902/jop.2011.110232
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.498-505
  • Anahtar Kelimeler: Alveolar bone loss, cathepsin K, dental implants, inflammation, tooth, GINGIVAL CREVICULAR FLUID, NITRIC-OXIDE METABOLISM, FOLLOW-UP, MATRIX METALLOPROTEINASES, EDENTULOUS PATIENTS, NATURAL TEETH, PERIODONTITIS, IMPACT, DISEASE, MYELOPEROXIDASE
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Cathepsin-K is an enzyme involved in bone metabolism which may make this feature important for both natural teeth and dental implants. The aims of the present study are to comparatively analyze the gingival crevicular fluid (GCF)/peri-implant sulcus fluid (PISF) cathepsin-K levels of natural teeth and dental implants, and to assess the potential relationship between this biochemical parameter and alveolar bone loss around natural teeth and dental implants.