Importance of cranial nerve involvement in nasopharyngeal carcinoma. A clinical study comprising 124 cases with special reference to clinical presentation and prognosis


Turgut M., Erturk O., SAYGI S., Ozcan O.

NEUROSURGICAL REVIEW, cilt.21, sa.4, ss.243-248, 1998 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1007/bf01105779
  • Dergi Adı: NEUROSURGICAL REVIEW
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.243-248
  • Anahtar Kelimeler: carcinoma, cranial nerve, computerized tomography, nasopharynx, pathology, THERAPY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

A review of nasopharyngeal carcinomas (NPCs) treated in the Hacettepe University Hospitals is presented. One hundred twenty-four patients between the ages of 3 years and 72 years were managed in the period 1968-1992. Of these cases, 48 had only cranial nerve (CN) involvement on admission. The most commonly affected CNs were the VIth and the Vth, in that order. The prognostic significance of this finding is obvious, because early diagnosis and treatment is vital in a cancer patient. This study includes retrospective analysis of 124 patients with NPC. The patients were investigated with respect to clinical and radiological diagnosis and outcome. Our results also show that CN involvement in NPC usually requires careful neuro-otological examination. It is suggested that increased knowledge and understanding of the disease among neurosurgeons, neurologists and ENT surgeons would improve the prognosis of patients with NPC.