Smooth Muscle Hyperplasia in an Asthmatic Patient: Do We Know It All?

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Ergan-Arsava B., KARAKAYA G., Firat P., KALYONCU A. F.

RESPIRATION, vol.81, no.2, pp.152-156, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 81 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.1159/000319551
  • Journal Name: RESPIRATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.152-156
  • Hacettepe University Affiliated: Yes


Bronchial smooth muscle hyperplasia is a well-known structural change in asthma. The degree of hyperplasia is related to asthma severity. We report a case of extreme smooth muscle hyperplasia in an asthmatic patient. A 54-year-old female with a diagnosis of analgesic-induced asthma was admitted to our center for nasal polyposis surgery. During her preoperative evaluation, atelectasis of the right middle lobe was detected on chest X-ray. Bronchoscopy revealed the presence of a vegetating polypoid mass obliterating the entrance of the right middle lobe. Histopathological examination of the surgically excised polypoid mass showed benign smooth muscle proliferation with diffuse eosinophilic infiltration. This is a rare case representing an extreme example of benign smooth muscle hyperplasia forming an endobronchial mass in an asthmatic patient. Copyright (C) 2010 S. Karger AG, Basel