MUC1 and bcl-2 Expression in Preinvasive Lesions and Adenosquamous Carcinoma of the Lung

Demirag F., Cakir E., Bayiz H., Yazici U. E.

ACTA CHIRURGICA BELGICA, vol.113, no.1, pp.19-24, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 113 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1080/00015458.2013.11680879
  • Journal Name: ACTA CHIRURGICA BELGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.19-24
  • Hacettepe University Affiliated: Yes

Abstract

Background : Adenosquamous carcinoma of the lung involves both adenocarcinoma and squamous cell carcinoma, each comprising at least 10% of the tumor. Atypical adenomatous hyperplasia (ADH), bronchiolar columnar cell dysplasia (BCCD), basal cell dysplasia (BCD), columnar cell dysplasia (CCD), bronchial epithelial dysplasia with transitional differentiation (BEDT) and squamous dysplasia (SD) are preinvasive lesions. The aim of this study is to define the preinvasive lesions and evaluate the role of MUC1, bcl-2, and the preinvasive and invasive components of adenosquamous carcinoma.